Rose F. Kennedy Center for Research in Mental Retardation and Developmental Disabilities

The Rose F. Kennedy Center for Research in Mental Retardation and Developmental Disabilities was established on July 1, 1970. The Center at the Albert Einstein College of Medicine (AECOM) was one of the initial twelve Mental Retardation Research Centers created under the provisions of Public Law 88 164, the Mental Retardation Facilities and Community Health Centers Construction Act of 1963. Since its inception, the Kennedy Center has been the focus of Neuroscience, Pediatric and Cognitive research at AECOM, and the only academic clinical facility addressing developmental disabilities for the extensive and largely under served populations of the Bronx. The Kennedy Center has a rich and proud history of excellence. It has been a site of breakthrough research in developmental neuroscience, has served as a unique site of training for students, fellows and residents in the clinical management of developmental disabilities, and has impacted the lives of countless individual children and their families.

The Kennedy Center is a ten-story structure comprising approximately 74,000 net square feet of research and clinical facilities. Center Investigators hold academic appointments in various basic science and clinical departments, including Neuroscience, Pediatrics, Neurology, Pathology, Otolaryngology, Molecular Genetics, and Ophthalmology.

The strength of the Center is based on both the excellence of the individual investigators and on their ability to develop and maintain strong collaborative research efforts. Investigators are independent scientists with federally funded research support and established records of research productivity. Funding sources include the NIH, as well as highly competitive private agencies. Kennedy Center investigators are also involved in funded clinical trials.

To maintain status as a Center Investigator, individual researchers must continue to demonstrate both success in strong “peer review” processes and relevance of their research to our understanding of mental retardation and developmental disabilities. A hallmark of the Center is the network of research programs organized around specific themes, but involving multiple investigators (often from different laboratories). We have strong, multi-investigator programs in:

  • Molecular and cellular bases of MRDD, including Fragile X and autism
  • Cellular and molecular aspects of brain development and plasticity
  • Neurogenetics and disease
  • Metabolic Storage Disorders and inborn effects
  • Neural protection and repair
  • Hypoxic damage to the nervous system and mechanisms of adaptation
  • Effects of hormones on neural function
  • Cortical physiology
  • Plasticity and regulation of synaptic transmission
  • Auditory processing in humans, cochlear implantation
  • Genetic models of cognition and behavior
  • Direct cellular communication
  • Pediatric seizure disorders, including diagnosis and therapy
  • Autism
  • Novel methodologies for screening patient populations, diagnosis and validation of emerging technologies